That seems to be the question being answered in the video B E A U T Y by Rino Stefano Tagliafierro. In it he takes many famous classical paintings and animates them with the results being both lovely and creepy. You will definitely want to watch this one full screen and in HD. Note: There’s some amount of nudity and violence in this so consider it NSFW:
One of the things that occurred to me as I watched this is that a lot of classic paintings have some pretty twisted subject matter to them that’s really highlighted when you animate it. Granted, the animation in this is somewhat limited, but even the small amounts that are done are impactful. You can find the full list of all the paintings used here.